Detroit Lions 2025 Opponents 2025. A look at the 14 opponents making up 17 games for the detroit lions during the 2025 regular season. View the 2025 detroit lions football schedule at fbschedules.com.

1 seed — we now know the full slate of opponents the detroit lions will face. The detroit lions 2025 opponents includes divisional rivals, top nfc east and afc north teams, and three division champions.